There is therefore now no condemnation for those who are in Christ Jesus. For the law of the Spirit of life in Christ Jesus has set you free from the law of sin and of death…. If the Spirit of him who raised Jesus from the dead dwells in you, he who raised Christ from the dead will give life to your mortal bodies also through his Spirit that dwells in you. (Romans 8:1-2, 11).
Human beings have two problems that are related. First, we are mortal. We will die.... as the adage goes, "Not one of us will get out of life alive." Second, we are flesh and for Paul that does not mean physical flesh covering bones, but living life that is not in character with God's will and desires for human beings. For Paul, life in the Spirit means that flesh and blood human beings can live a life that is not according to the flesh.